Selected Publications
Reinstatement of nicotine conditioned place preference in a transgenerational model of drug abuse vulnerability in psychosis: Impact of BDNF on the saliency of drug associations
Modulation of mGlu5 improves sensorimotor gating deficits in rats neonatally treated with quinpirole through changes in dopamine D2 signaling
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Peeters LD, Wills LJ, Cuozzo AM, Ivanich KL, Brown RW. Reinstatement of nicotine conditioned place preference in a transgenerational model of drug abuse vulnerability in psychosis: Impact of BDNF on the saliency of drug associations. Psychopharmacology. https://doi.org/10.1007/s00213-023-06379-7
Brown, R. W., Varnum, C. G., Wills, L. J., Peeters, L. D., & Gass, J. T. (2021). Modulation of mglu5 improves sensorimotor gating deficits in rats neonatally treated with Quinpirole through changes in dopamine D2 signaling. Pharmacology Biochemistry and Behavior, 211, 173292. https://doi.org/10.1016/j.pbb.2021.173292
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Transgenerational evidence of increases in dopamine D2 receptor sensitivity in rodents: Impact on sensorimotor gating, the behavioral response to nicotine and BDNF
The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole
Effects of an adenosine A2A agonist on the rewarding associative properties of nicotine and neural plasticity in a rodent model of schizophrenia
Ciliary neurotrophic factor is a key sex-specific regulator of depressive-like behavior in mice
Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders
Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia
Antidepressant-Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models
Elevated DNA Oxidation and DNA Repair Enzyme Expression in Brain White Matter in Major Depressive Disorder
The effects of adolescent methylphenidate exposure on the behavioral and brain-derived neurotrophic factor response to nicotine
Perinatal Treatments with the Dopamine D₂-Receptor Agonist Quinpirole Produces Permanent D₂-Receptor Supersensitization: a Model of Schizophrenia
Effects of sarizotan in animal models of ADHD: challenging pharmacokinetic-pharmacodynamic relationships
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Gill, W. D., Burgess, K. C., Vied, C., & Brown, R. W. (2021). Transgenerational evidence of increases in dopamine D2 receptor sensitivity in rodents: Impact on sensorimotor gating, the behavioral response to nicotine and BDNF. Journal of Psychopharmacology, 35(10), 1188-1203. https://doi.org/10.1177/02698811211033927
Brown, R. W., Bhide, P. G., Gill, W. D., & Peeters, L. D. (2020). The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with Quinpirole. Psychopharmacology, 237(12), 3519–3527. https://doi.org/10.1007/s00213-020-05631-8
Gill, W. D., Shelton, H. W., Burgess, K. C., & Brown, R. W. (2019). Effects of an adenosine a2a agonist on the rewarding associative properties of nicotine and neural plasticity in a rodent model of schizophrenia. Journal of Psychopharmacology, 34(1), 137–144. https://doi.org/10.1177/0269881119885917
Jia C, Brown RW, Malone HM, Burgess KC, Gill WD, Keasey MP, Hagg T. Ciliary neurotrophic factor is a key sex-specific regulator of depressive-like behavior in mice. Psychoneuroendocrinology. 2019 Feb;100:96-105. 10.1016/j.psyneuen.2018.09.038
Kostrzewa RM, Wydra K, Filip M, Crawford CA, McDougall SA, Brown RW, Borroto-Escuela DO, Fuxe K, Gainetdinov RR. Dopamine D(2) Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders. J Pharmacol Exp Ther. 2018 Sep;366(3):519-526. 10.1124/jpet.118.247981
Brown RW, Schlitt MA, Owens AS, DePreter CC, Cummins ED, Kirby SL, Gill WD,Burgess KC. Effects of Environmental Enrichment on Nicotine Sensitization in RatsNeonatally Treated with Quinpirole: Analyses of Glial Cell Line-DerivedNeurotrophic Factor and Implications towards Schizophrenia. Dev Neurosci.2018;40(1):64-72. 10.1159/000486391
Ordway GA, Szebeni A, Hernandez LJ, Crawford JD, Szebeni K, Chandley MJ, Burgess KC, Miller C, Bakkalbasi E, Brown RW. Antidepressant-Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models. Int J Neuropsychopharmacol. 2017 Dec 1;20(12):994-1004. 10.1093/ijnp/pyx068
Szebeni A, Szebeni K, DiPeri TP, Johnson LA, Stockmeier CA, Crawford JD, Chandley MJ, Hernandez LJ, Burgess KC, Brown RW, Ordway GA. (2017). Elevated DNA Oxidation and DNA Repair Enzyme Expression in Brain White Matter in Major Depressive Disorder. International Journal of Neuropsychopharmacology. 20(5):363-373. 10.1093/ijnp/pyw114
Cummins ED, Leedy KK, Dose JM, Peterson DJ, Kirby SL, Hernandez LJ, Brown RW. (2017). The effects of adolescent methylphenidate exposure on the behavioral and brain-derived neurotrophic factor response to nicotine. Journal of Psychopharmacology. 31(1):75-85.
https://doi.org/10.1177/0269881116681458 Kostrzewa RM, Nowak P, Brus R, Brown RW. (2016). Perinatal Treatments with the Dopamine D-Receptor Agonist Quinpirole Produces Permanent D-Receptor Supersensitization: a Model of Schizophrenia. Neurochemical Research. 41(1-2):183-92.
10.1007/s11064-015-1757-0 Danysz, W., Fink, G., McCreary, A., Tober, C., Dimpfel, W., Bizot, J. C., Kostrzewa, R. M., Brown, R. W., Jetzke, C. C., Greco, S., Jensen, A. K., Parsons, C. G. (2015). Effects of sarizotan in animal models of ADHD challenging PK-PD relationship. Journal of Neural Transmission Mar 22.
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